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Hallucinogens, including LSD, do not induce addiction in the same manner as opioids and alcohol, as they do not impact dopamine levels or the brain’s “reward” center. Nonetheless, frequent LSD use can lead to an increase in tolerance. Tolerance and addiction represent distinct states, each accompanied by different withdrawal symptoms. Long-term LSD users may occasionally encounter hallucinogen-persisting perception disorder (HPPD or “flashbacks”), reminiscent of an LSD trip without ingesting the drug.
Building tolerance to Ecstasy can result in withdrawal symptoms, making it potentially more addictive than other hallucinogens. Withdrawal may cause depression, anxiety, fatigue, cognitive difficulties, and cravings, potentially leading to further substance abuse.